The FDA has approved three PrEP options for preventing HIV infection:

• Truvada: Daily pill recommended for adolescents and adults at risk of HIV infection through sex or injection drug use.
• Descovy: Daily pill recommended for adolescents and adults at risk of HIV infection through sex or injection drug use. Not to be used in people assigned female at birth who are at risk of getting HIV from vaginal sex because its effectiveness has not been studied in this group of people.
• Apretude: A shot that is taken every two months and recommended for adolescents and adults at risk for HIV infection through sex or injection drug use.

PrEP is highly effective when taken as prescribed. Oral PrEP has been shown to reduce the risk of getting HIV from sex by 99%, and by 84% among those who inject drugs. The effectiveness of both the pill and the shot is reduced when not taken as prescribed.

PrEP does not protect you from other sexually transmitted infections like chlamydia, gonorrhea, or syphilis, so you should use PrEP together with condoms. PrEP can be taken with birth control or hormone therapy.

If you decide to use PrEP, you must commit to taking the medication as prescribed—daily for oral PrEP or every two months for injectable PrEP. Additionally, you should schedule regular follow-up appointments with a healthcare provider every 2 to 3 months to talk about any side effects or symptoms. Your provider will also test you for HIV and other STIs.

In Philadelphia, most people can get PrEP for little or no cost, even if they don’t have insurance. Talk to your doctor or visit one of the sites on this map.

• Provider directory
• Learn more about medical providers that offer PrEP to eligible patients.

You can also receive oral PrEP medications through a virtual appointment with some providers across the city. This a convenient way to ensure you continue to get your pills. Schedule a virtual appointment.